
San Antonio sits on the ancestral lands of the Payaya, Coahuiltecan, and other Indigenous peoples who inhabited the region for over 10,000 years. The Spanish colonial mission system, beginning with the establishment of Mission San Antonio de Valero (the Alamo) in 1718 and four other missions along the San Antonio River, subjected Indigenous populations to forced labor, religious indoctrination, and systematic cultural erasure. Franciscan missionaries, backed by Spanish military garrisons, compelled Indigenous people to abandon their traditional lifeways and work as agricultural laborers and masons building the mission compounds. The mission system served as an instrument of colonial domination, with Indigenous populations declining by over 70 percent due to introduced European diseases, malnutrition from forced labor regimens, and violent suppression of resistance. The Spanish Inquisition's reach extended to San Antonio, where Indigenous people found practicing traditional ceremonies were subjected to public floggings and imprisonment.
Following Mexican independence from Spain in 1821, the secularization of mission lands promised to return territory to Indigenous communities, but instead these lands were rapidly acquired by Anglo-American settlers flooding into Texas under empresario colonization schemes. The Texas Revolution of 1835-1836, mythologized in US popular culture as a noble struggle for freedom, was in reality a settler colonial rebellion driven by Anglo-American slaveholders' desire to preserve and expand the institution of slavery. The Alamo, portrayed as a heroic last stand, was a strategic outpost where primarily Anglo settlers and adventurers fought against the Mexican Army under General Antonio Lopez de Santa Anna. The Mexican government had outlawed slavery in 1829, directly threatening the economic interests of Anglo settlers who had brought enslaved Black people into Texas. The Texas Declaration of Independence explicitly cited Mexico's abolitionist policies as a grievance. Tejano residents of San Antonio-Mexican-born Texans who had lived in the region for generations-were caught in the crossfire, with many forced to choose sides or face reprisals from both Anglo and Mexican forces.
The US annexation of Texas in 1845 and the subsequent Mexican-American War (1846-1848) formalized the dispossession of San Antonio's Tejano and Mexican-origin population. The Treaty of Guadalupe Hidalgo guaranteed property rights for Mexican citizens in the newly acquired territories, but in practice, Tejano landowners in Bexar County faced systematic legal theft of their lands through the Texas land commission system. Property taxes, legal fees conducted entirely in English, and fraudulent surveys stripped Tejano families of their ancestral ranchos. The establishment of the US Army's Fort Sam Houston in 1845 consolidated federal military power in the region, used not only for frontier defense but for enforcing the new Anglo-dominated legal order. During the Civil War (1861-1865), San Antonio served as a Confederate supply depot and center for cotton smuggling through Mexico, enriching the Anglo elite while Tejano and Black communities bore the costs of the war. After Reconstruction, San Antonio's Mexican-American community was systematically excluded from political power through poll taxes, literacy tests, and Anglo-dominated political machines.
San Antonio enforced a rigid system of Jim Crow segregation that targeted both African American and Mexican American communities. Despite being legally classified as white under Texas law, Mexican Americans faced de facto segregation in housing, education, employment, and public accommodations. The city's east side became a segregated Black neighborhood, while west-side barrios confined Mexican American families to substandard housing with inadequate infrastructure. In 1910, San Antonio police were implicated in the torture of Gregorio Cortez, a Mexican American folk hero whose case exposed systemic law enforcement brutality. The 1910s and 1920s saw a wave of lynchings and extrajudicial killings of Mexican Americans along the Rio Grande border region, with San Antonio serving as a staging ground for Texas Rangers who operated as a paramilitary force targeting the Mexican-origin population. School segregation remained official policy until the 1954 Brown v. Board of Education decision, but San Antonio's schools remained effectively segregated through housing patterns well into the 1970s. Police brutality against the Mexican American community was documented by the 1943 Sleepy Lagoon defense committee and the 1948 American GI Forum, both civil rights organizations founded by Mexican American veterans.
The establishment of Fort Sam Houston, Lackland Air Force Base (1941), Brooks Air Force Base, and Randolph Air Force Base transformed San Antonio into one of the most militarized cities in the United States, with the military becoming the largest employer. This military-industrial complex has been a double-edged sword for San Antonio's communities of color: providing employment while simultaneously funneling working-class youth into imperial wars, disproportionately targeting Black and Latino communities for military recruitment. The federal urban renewal programs of the 1950s and 1960s targeted San Antonio's west-side barrios, displacing thousands of Mexican American families under the guise of slum clearance. The construction of the HemisFair complex for the 1968 World's Fair destroyed the predominantly Mexican American neighborhood of La Villita, displacing centuries-old Tejano communities to make way for tourist development. In the 1970s, the Chicano Movement in San Antonio organized against police brutality, educational inequality, and political exclusion. The 1970s and 1980s saw a wave of police brutality scandals, including the 1977 death of Jose Campos in police custody. Modern San Antonio remains deeply segregated along class and racial lines, with the military and tourism industries dominating the economy while low-income communities of color bear the brunt of environmental racism from industrial pollution on the city's south and east sides.